Origin
Japan
Usually seen smiling, Maria is one of the central characters of the series. Two years ago during the events of 428: Fūsasareta Shibuya de, she was abducted by terrorists and was infected with the Ua virus, surviving the ordeal only thanks to the anti-virus her father developed. She befriended Canaan after being saved from hoodlums during a trip somewhere in the Middle East. As her dream is to become a photographer, she became the partner of Minoru Minorikawa before the pair's assignment in Shanghai and her subsequent reuniting with Canaan. Despite being aware of Canaan's dangerous life, Maria tries her best to stay close to her friend. Many characters have made fun of her ahoge hairstyle and her relatively small bust size.

Canaan
Oosawa Maria is a Japanese photographer currently working in Shanghai, China. Along with her partner Mino, she searches for potential newsworthy stories throughout the city. When strange events occur at a local festival, Maria and Mino immediately investigate. Quickly, the two are immersed in a battle between unknown masked men and a strange, white-haired woman. Just when Maria is about to be caught in the crossfire, an old friend by the name of Canaan appears and helps Maria escape. But a sinister plot over a deadly virus soon develops, and Canaan learns she must confront her past if she wants any chance at stopping the perpetrator and saving her friends.