Nanako Mizuki (水樹 ななこ, Mizuki Nanako) appears in first episode at the very start of GTO series who is Eikichi Onizuka's next big challenge at Musashino. She lured him into a trap in an attempt to try to get some money out of him (along with the 3 punks of Class O), but Onizuka didn't go down. At around the same time, she tried to reach out and get some help. With her family life deteriorating, she felt that Onizuka could fill that void. Ultimately, Onizuka did something to help her out, demonstrating his abnormal strength by destroying a part of wall which was to symbolize the distance she was feeling between her and her family. After that, she fell in love (sort of) to Onizuka, she said that when he becomes the greatest teacher in Tokyo she will be waiting for him.

Great Teacher Onizuka (GTO)
Twenty-two-year-old Eikichi Onizuka—ex-biker gang leader, conqueror of Shonan, and virgin—has a dream: to become the greatest high school teacher in all of Japan. This isn't because of a passion for teaching, but because he wants a loving teenage wife when he's old and gray. Still, for a perverted, greedy, and lazy delinquent, there is more to Onizuka than meets the eye. So when he lands a job as the homeroom teacher of the Class 3-4 at the prestigious Holy Forest Academy—despite suplexing the Vice Principal—all of his talents are put to the test, as this class is particularly infamous. Due to their utter contempt for all teachers, the class' students use psychological warfare to mentally break any new homeroom teacher they get, forcing them to quit and leave school. However, Onizuka isn't your average teacher, and he's ready for any challenge in his way. Bullying, suicide, and sexual harassment are just a few of the issues his students face daily. By tackling the roots of their problems, Onizuka supports them with his unpredictable and unconventional methods—even if it means jumping off a building to save a suicidal child. Thanks to his eccentric charm and fun-loving nature, Class 3-4 slowly learns just how enjoyable school can be when you're the pupils of the Great Teacher Onizuka. [Written by MAL Rewrite]