Shirube Asube is the heroine of Girls' Work. Shirube is a second year middle school student. She is a rebel child and a wild girl who symbolizes the vitality and freedom of Shinjuku. She exerts influence in any level of the city, and she's feared and called "The Holy Mother". Non-humans who lurk in the city refer to her mysterious existence as "The Heart of the City" and acknowledge her superiority. She plays around, flying through the city as if it were her own dedicated amusement park. She has a whimsical temper and a sharp tongue. She's an arrogant child, and due to being a rebel, doesn't have any friends her own age. She enjoys the stimulus of opposed extreme flavors, such as strong carbonated sodas and sweets, and cold things and hot, spicy things.

Girls' Work
All that is currently [January 2021] known about the scenario taking place in Girls' Work is that the story involves a version of Shinjuku that has "become one" with Paris. The city is called "the city that dreams", and is mentioned to be the real main character of the story.